A number of New Patriotic Party (NPP) parliamentarians have been voted out in the party’s primaries, ceding the right to contest in the 2020 general elections to newcomers.
Some new entrants include Dickson Adomako Kissi for the Anyaa Sowutuom constituency, Ekow Vincent Assafuah for the Old Tafo constituency and Alhaji Farouk Aliu Mahama, Yendi.
| CONSTITUENCY | INCUMBENT MP | NEWBIE |
| 1. Bantama | Daniel Okyem Aboagye | Asenso Boakye |
| 2. Tema Central | Kofi Brako | Yves Hanson-Nortey |
| 3. Manyhia North | Collins Owusu Amankwa | Akwasi Konadu |
| 4. Nhyiaeso | Kennedy Kankam | Stephen Amoah |
| 5. La Dadekotopon | Vincent Sowah | Gerald Joseph Nyanyofio |
| 6. Kwesimintsim | Joseph Mensah | Prince H Armah |
| 7. Okaikwei South | Ahmed Arthur | Darkoa Newman |
| 8. Ablekuma North | Nana Akua Afriyie | Sheila Bartels |
| 9. Akwatia | Ama Sey | Ernest Yaw Kumi |
| 10. Bibiani-Anwiaso-Bekwai | Kingsley Aboagye Gyedu | Alfred Obeng Boateng |
| 11. Ejisu | Kwabena Owusu Aduomi | John Kumah |
| 12. Akim Oda | William Agyapong Quaitoo | Alexander Akwasi Acquah |
| 13. Navrongo Central | Kofi Adda | Tangoba Abayage |
| 14. Sissala West | Patrick Adamah | Nalewie Baluwie |
| 15. New Juaben South | Mark Assibey Yeboah | Michael Okyere Baafi |
| 16. Wa East | Godfred Bayon Tangu | Ing. Salifu Yakubu |
| 17. Saboba | Charles Bintin Binipom | |
| 18. Sissala East | Ridwan Abass | Issahaku Amidu Chinnia |
| 19. Shama | Ato Panford | Samuel Ericson Abaka |
| 20. Mpohor | Alex. K. Agyekum | John Kobina Abbam Aboah Sanie |
| 21. Nsuta kwamang-Biposo | Kwame Asafu Adjei | Adelaide Yaa Agyeiwaa Ntim |
| 22. Walewale | Dr Sagri Bambangi | Hajia Lariba Abudu |
| 23. Tolon | Wahab Suhiyini Wumbei | Habib Iddrisu |
| 24. Nkawkaw | Erick kwakye Daffour | Joesph Frimpong |
| 25. Bortianor Ngleshie Amanfro | Saad Habiab | Sylverster Tetteh |
| 26. Amenfi East | Partrick Kwame Bogyako Saim | Edward Amo Kow |
| 27. Asutifi North | Joseph Daha | Patrick Bannor |
| 28. Asikuma Odoben Brakwa | Anthony Effah | Emmanuel Adjei Domson |
| 29. Atwima-Kwanwoma | Dr Kojo Appiah-Kubi | Nana Kwaku Owusu Acheampong |
| 30. Suhum | Fredrick Opare Ansah | Kwadwo Asante |
| 31. Asutifi North | Benhazin Joseph Dahah | Patrick Bannor |
| 32. Manso Nkwanta | Joseph Albert Quarm | George Obeng |
| 33. Tolon | Wahab Suhiyini Wumbei | Habib Iddrisu |
| 34. Berekum East | Dr Kwabena Twum-Nuamah | Nelson Kyeremeh |
| 35. Dormaa East | William Kwasi Sabi | Paul Twum |
| 36. Offinso South | Abdallah Banda |
Some incumbent Members of Parliament have secured the slot to contest the 2020 parliamentary contest on behalf of the NPP. A few more constituencies are yet to conduct their primaries.
| MEMBER OF PARLIAMENT (MP) | CONSTITUENCY |
| 1. Mr Salifu Adam Braimah | Salaga South |
| 2. Yaw Buaben Asamoa | Adentan |
| 3. Sarah Adwoa Safo | Dome-Kwabenya |
| 4. K.T. Hammond | Adansi Asokwa |
| 5. Titus Glover | Tema East |
| 6. John Osei-Frimpong | Abirem |
| 7. Dr Afriyie Nana Ayew | Effiduase-Asokore |
| 8. Elizabeth Afoley Quaye | Krowor |
| 9. Kofi Okyere Agyekum | Fanteakwa South |
| 10. Joseph Cudjoe | Effia |
| 11. Emmanuel Marfo | Oforikrom |
| 12. Philip Basoah | Kumawu |
| 13. Martin Oti Gyarko | Techiman North |
| 14. George Nenyi Andah | Awutu Senya West |
| 15. OB Amoah | Akwapim South |
| 16. Major Derick Oduro (RTD) | Nkoranzah North |
| 17. Kwasi Ameyaw Cheremeh | Sunyani East |
| 18. Carlos Ahenkorah | Tema West |
| 19. Frank Fuseini Adongo | Zebilla |
| 20. Ebenezer Kojo Kum | Ahanta West |
| 21. Elvis Morris Donkoh | Abura- Asebu Kwamankese |
| 22. Anthony Abayifaa Karbo | Lawra |
| 23. Kwaku Ampratwum Sarpong | Mampong |
| 24. Cynthia Mamle Morrison | Agona West |
| 25. Amma Pomaah Boateng | Juaben |
| 26. Ekow Kwansah Hayford | Mfantseman |
| 27. Kwaku Asante-Boateng | Asante Akim South |
| 28. Issah Fuseini | Okaikwei North |
| 29. Kwabena Okyere Darko-Mensah | Takoradi |
| 30. Evans Opoku Bobbie | Asunafo North |
| 31. Charles Konadu | Nkoranza South |
| 32. Prof. Gyan Baffour | Wenchi |
| 33. Yaw Afful | Jaman South |
| 34. Samuel Aye-Paye | Ayensuano |
| 35. Barbara Asher Ayisi | Cape Coast North |
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